Arthritis Medications

Physicians usually start with drugs which have the fewest side effects. As the arthritis progresses, you may need stronger medications.
Non steroidal anti inflammatory drugs are usually the drugs of first choice. These drugs help decrease inflammation and reduce pain. Over the counter medications like Ibuprofen or Aleve do help but most people require stronger prescription painkillers like Celebrex or tramadol. While these drugs are effective, they are also associated with a variety of side effects like abdominal pain, bleeding, ulcers, liver and kidney damage. Non steroidal anti inflammatory drugs should not be used for prolonged periods without proper physician supervision.

Corticosteroids are frequently prescribed for individuals with arthritis. These potent drugs can help reduce inflammation and slow down joint damage. However, corticosteroids have potent side effects which range from ulcer, skin bruising, weight gain, cataracts, bone thinning, diabetes and hypertension. Corticosteroids are usually given for a short time to help reduce acute symptoms.

Disease-modifying antirheumatic drugs (DMARDs) can help slow down progression of rheumatoid arthritis and joint damage. The most common DMARDs include methotrexate (Rheumatrex, Trexall), leflunomide (Arava), hydroxychloroquine (Plaquenil), sulfasalazine (Azulfidine) and minocycline (Dynacin, Minocin). All these drugs have side effects which include liver damage, bone marrow suppression and possibility of opportunistic infections.

Immunosuppressants like cyclosporine and cyclophosphamide suppress potent cells of the body and help decrease the inflammation. These medications do help treat severe arthritis but also make one prone to infections.

Tumor necrosis factor inhibitors have been shown to reduce inflammation, pain, morning stiffness and swelling of joints. Drugs like etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira) can significantly improve quality of life. The most common side effects from these drugs include pain at site of injection, heart failure and increased risk of infection.

Source: http://en.wikipedia.org/wiki/Arthritis